Progress in Basic Research and Clinical Treatment of Multiple Pulmonary Nodules.
10.3779/j.issn.1009-3419.2019.03.10
- Author:
Xuejie WU
1
;
Donglai CHEN
2
;
Rongying ZHU
1
;
Yifei WANG
1
;
Chang CHEN
2
;
Yongbing CHEN
1
;
Wentao YANG
1
Author Information
1. Department of Thoracic Surgery, the Second Affiliated Hospital of Soochow University, Suzhou 215000, China.
2. Department of
Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China.
- Publication Type:Journal Article
- Keywords:
Genomic sciences;
Lung neoplasms;
Multiple pulmonary nodules;
Surgical treatment
- MeSH:
Diagnostic Imaging;
Genotype;
Humans;
Multiple Pulmonary Nodules;
diagnostic imaging;
genetics;
therapy
- From:
Chinese Journal of Lung Cancer
2019;22(3):173-177
- CountryChina
- Language:Chinese
-
Abstract:
Lung cancer leads to the highest cancer-related morbidity and mortality worldwide. With the development of multi-slice spiral computed tomography technology and the implement of lung cancer screening, more and more lung nodules have been discovered, many of which are multiple pulmonary nodules. These pulmonary nodules are usually diagnosed as multiple primary lung adenocarcinomas from a pathological perspective. For multiple nodules with different imaging features, the preferred treatment methods are different, and the treatment of each lung nodule is still controversial. In recent years, the interactions between multiple lesions and the evolution of the lesions as well as the inter-tumoral and intratumoral homogeneity and heterogeneity of the genomics also arouse attention. Our review gathered the research progress in multiple pulmonary nodules from the points of histopathology, genomics and surgical management.
.