Clinical Diagnosis and Treatment Recommendations for Ocular Toxicities of Target Therapy and Immune Checkpoint Inhibitor Therapy.
10.3779/j.issn.1009-3419.2019.10.09
- Author:
Xiaowei LIU
1
;
Zheng WANG
2
;
Chan ZHAO
1
;
Hanping WANG
3
;
Xiaoxiao GUO
4
;
Jiaxin ZHOU
5
;
Lian DUAN
6
;
Xiaoyan SI
3
;
Li ZHANG
7
;
Yue LI
8
;
Mengzhao WANG
3
;
Juhong SHI
3
;
Meifen ZHANG
1
;
Li ZHANG
3
Author Information
1. Department of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
2. Department of Ophthalmology, Beijing Hospital, Beijing 100730, China.
3. Department of Respiratory Medicine, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
4. Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
5. Department of Rheumatology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
6. Department of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
7. Department of Clinical Laboratory, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
8. Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
- Publication Type:Journal Article
- Keywords:
Immune checkpoint inhibitor;
Immunotherapy-related toxicities;
Ocular diseses;
Target therapy
- From:
Chinese Journal of Lung Cancer
2019;22(10):653-660
- CountryChina
- Language:Chinese
-
Abstract:
The increasing use of target therapy and immunocheckpoint inhibitors in cancers has brought new hope of survival to patients with advanced tumors. However, more and more adverse side-effects and toxicities of these medications had been reported, affect almost all human organs including the eye. These adverse effects may affect the entire ocular tissues, like eyelid, eye lashes, conjunctiva, cornea, uvea, retina, optic nerve and so on, which are always been ignored by patients and doctors. In this paper we will summarize the characteristics of the related ocular diseases and give our advice on how to diagnose and manage these diseases.
