Autonomic Disturbances in Acute Cerebrovascular Disease.
10.1007/s12264-018-0299-2
- Author:
Jun MO
1
;
Lei HUANG
2
;
Jianhua PENG
2
;
Umut OCAK
2
;
Jianmin ZHANG
3
;
John H ZHANG
4
Author Information
1. Department of Neurosurgery, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, 322000, China.
2. Department of Physiology and Pharmacology, Loma Linda University, Loma Linda, CA, 92350, USA.
3. Department of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, China. zjm135@zju.edu.cn.
4. Department of Physiology and Pharmacology, Loma Linda University, Loma Linda, CA, 92350, USA. johnzhang3910@yahoo.com.
- Publication Type:Journal Article
- Keywords:
Autonomic disturbance;
Autonomic nervous system;
Cerebrovascular disease;
Stroke
- MeSH:
Acute Disease;
Animals;
Autonomic Nervous System;
physiopathology;
Cerebrovascular Disorders;
complications;
physiopathology;
Humans;
Nerve Net;
injuries;
Sensorimotor Cortex;
physiopathology;
Stroke;
physiopathology
- From:Neuroscience Bulletin
2019;35(1):133-144
- CountryChina
- Language:English
-
Abstract:
Autonomic disturbances often occur in patients with acute cerebrovascular disease due to damage of the central autonomic network. We summarize the structures of the central autonomic network and the clinical tests used to evaluate the functions of the autonomic nervous system. We review the clinical and experimental findings as well as management strategies of post-stroke autonomic disturbances including electrocardiographic changes, cardiac arrhythmias, myocardial damage, thermoregulatory dysfunction, gastrointestinal dysfunction, urinary incontinence, sexual disorders, and hyperglycemia. The occurrence of autonomic disturbances has been associated with poor outcomes in stroke patients. Autonomic nervous system modulation appears to be an emerging therapeutic strategy for stroke management in addition to treatments for sensorimotor dysfunction.
