Application of fingerprint technology in quality evaluation and process control of traditional Chinese medicine formula granules.
10.19540/j.cnki.cjcmm.20180703.008
- Author:
Hui ZHANG
1
;
Yan CHEN
1
;
Jia-Nan WANG
1
;
Hui-Jie JIANG
1
;
Xiao-Wei SHEN
1
;
Ji-Zhong YAN
1
Author Information
1. Zhejiang University of Technology, Hangzhou 310014, China.
- Publication Type:Journal Article
- Keywords:
GC;
HPLC;
IR;
TLC;
fingerprint;
process control;
quality evaluation;
traditional Chinese medicine formula granules
- MeSH:
Chromatography, High Pressure Liquid;
Chromatography, Thin Layer;
Drugs, Chinese Herbal;
standards;
Medicine, Chinese Traditional;
Quality Control
- From:
China Journal of Chinese Materia Medica
2018;43(19):3822-3827
- CountryChina
- Language:Chinese
-
Abstract:
The fingerprint technology could reflect the internal chemical characteristics of Chinese herbal medicine or preparation, which has the characteristics of "wholeness" and "fuzziness". It is suitable for evaluating the quality of intermediate and finished products in the production process of traditional Chinese medicine formula granules. In this paper, the applications of high performance liquid chromatography (HPLC), thin layer chromatography (TLC), gas chromatography (GC) and infrared spectrum (IR) fingerprint technology in the quality control of traditional Chinese medicine formula granules were reviewed, and their advantages and disadvantages were analyzed. The aim of this article is to enhance the combined application of various fingerprint technologies in traditional Chinese medicine formula granules. It could provide technical reference for realizing the stability of production process and improving the overall quality of formula granules.
