Phytochemical and pharmacological progress on humulane-type sesquiterpenoids.

Author: Shun-Gang JIAO ¹ ; Rui-Fei ZHANG ¹ ; Jun-Jun LI ¹ ; Sha-Na WUKEN ¹ ; He-Xin-Ge ZHANG ¹ ; Peng-Fei TU ¹ ; Xing-Yun CHAI ¹
Author Information

1. Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.
Publication Type:Journal Article
Keywords: chemical constituents; humulane; pharmacological activities; sesquiterpenoid
MeSH: Anti-Bacterial Agents; Antiviral Agents; Drugs, Chinese Herbal; Phytochemicals; Sesquiterpenes; chemistry; Structure-Activity Relationship
From: China Journal of Chinese Materia Medica 2018;43(22):4380-4390
CountryChina
Language:Chinese
Abstract: Humulane-type sesquiterpenoids, widely distributed in plants and microbes, include three types: α-humulene, β-humulene, and γ-humulene. Up to now, 98 humulane-type sesquiterpenoids have been reported, which possessed anti-tumor, anti-inflammatory, antibacterial, and antiviral activities. Herein, this paper describes their chemical constituents and pharmacological activities, hoping to bring benefits for further research and lay a foundation for investigating the structure-activity relationships.