Clinical features and prognosis of cervical adenocarcinoma and adenosquamous carcinoma: an analysis of 237 cases.
- Author:
Qian CHEN
1
;
Lu LIU
1
;
Jingjing ZHANG
1
;
Sai HAN
1
;
Baoxia CUI
1
;
Youzhong ZHANG
1
;
Beihua KONG
1
Author Information
1. Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan 250012, China.
- Publication Type:Journal Article
- MeSH:
Adenocarcinoma;
diagnosis;
mortality;
Carcinoma, Adenosquamous;
diagnosis;
mortality;
Female;
Humans;
Neoplasm Staging;
Prognosis;
Retrospective Studies;
Survival Rate;
Uterine Cervical Neoplasms;
diagnosis;
mortality
- From:
Journal of Zhejiang University. Medical sciences
2018;47(4):357-361
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyze the clinical features and prognosis of cervical adenocarcinoma (AC) and adenosquamous carcinoma of cervix (ASC).
METHODS:The clinical data of 237 patients, including 201 cases of AC and 36 cases of ASC (FIGO stage ⅠB1-ⅡA), who underwent surgery in Qilu Hospital between September 2007 and September 2016 were reviewed. Clinical features of two groups were compared, and Kaplan-Meier survival analysis was performed to evaluate the prognosis.
RESULTS:A larger proportion of ASC patients had lymphovascular space invasion compared with AC patients (<0.01), but no significant differences were observed in the age, FIGO stage, size of tumor, depth of stromal invasion, parametrial invasion, lymphatic metastasis and risk grade between two groups (all >0.05). The 5-year overall survival rates of AC and ASC groups were 79.4% and 78.3%, and the 5-year recurrence-free survival rates were 77.4% and 73.0%. Among patients received concurrent chemoradiotherapy, the 5-year overall survival rates were 71.0% and 61.4%, and the 5-year recurrence-free survival rates were 68.8% abd 61.1%, respectively. No significant differences were observed in 5-year overall survival rates and recurrence-free survival rates between AC and ASC patients (all >0.05).
CONCLUSIONS:Lymphovascular space invasion was more likely to occur in patients with ASC, but there was no significant difference in the prognosis between AC and ASC patients.
