Research progress on oxidative stress in pathogenesis of endometriosis.
- Author:
Jiayi HE
1
;
Xinmei ZHANG
1
Author Information
1. Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.
- Publication Type:Journal Article
- MeSH:
Antioxidants;
metabolism;
Endometriosis;
physiopathology;
Female;
Humans;
Oxidative Stress;
Reactive Oxygen Species;
metabolism
- From:
Journal of Zhejiang University. Medical sciences
2018;47(4):419-425
- CountryChina
- Language:Chinese
-
Abstract:
A large number of studies have shown that the oxidative imbalance is common in patients with endometriosis. Abnormal respiratory chain of mitochondrial, estrogen metabolism imbalance, iron overload, and ectopic foci may increase active oxygen, reduction of antioxidant enzyme and non-enzymatic substances may result in decreased antioxidant level, and the exposure to environmental hazards may further aggravate oxidative imbalance in patients with endometriosis. This article analyzes the oxidative imbalance and its role in the pathogenesis of endometriosis from the aspects of excessive oxide production and decreased antioxidant capacity.
