Research progress on interleukin-6 in lung cancer.
- Author:
Hexiao TANG
1
;
Yuquan BAI
1
;
Wulin SHEN
1
;
Jinping ZHAO
1
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
- Publication Type:Journal Article
- MeSH:
Disease Progression;
Humans;
Interleukin-6;
metabolism;
Lung Neoplasms;
physiopathology;
Neoplastic Stem Cells;
pathology;
Research;
trends;
T-Lymphocytes;
metabolism
- From:
Journal of Zhejiang University. Medical sciences
2018;47(6):659-664
- CountryChina
- Language:Chinese
-
Abstract:
As the core of cellular immunotherapy, T cells are important aspects of research and treatment of lung cancer. IL-6 is a costimulatory signal factor of T cells that is directly targeted by lung cancer stem cells. As a highly expressed cytokine in lung cancer cells, IL-6 plays an important role in variety of biological activities such as tumor occurrence, development, invasion and metastasis. This article reviews the research progress on IL-6 in lung cancer, including cancer development and progression, and the therapeutic sensitivity of lung cancer.
