Effects of emergency medical service on prognosis of ischemic stroke patients treated with intravenous thrombolysis.
- Author:
Wansi ZHONG
1
;
Zhicai CHEN
1
;
Hongfang CHEN
2
;
Dongjuan XU
3
;
Zhimin WANG
4
;
Haifang HU
5
;
Chenglong WU
6
;
Xiaoling ZHANG
7
;
Xiaodong MA
8
;
Yaxian WANG
9
;
Haitao HU
1
;
Min LOU
1
Author Information
1. Department of Neurology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
2. Department of Neurology, Jinhua Hospital of Zhejiang University, Jinhua Municipal Central Hospital, Jinhua 321000, Zhejiang Province, China.
3. Department of Neurology, Dongyang People's Hospital, Dongyang 322100, Zhejiang Province, China.
4. Department of Neurology, Taizhou First People's Hospital, Taizhou 318020, Zhejiang Province, China.
5. Department of Neurology, the First People's Hospital of Xiaoshan District, Hangzhou 311201, China.
6. Department of Neurology, Shaoxing People's Hospital, Shaoxing 312000, Zhejiang Province, China.
7. Department of Neurology, Jiaxing Second Hospital, Jiaxing 314000, Zhejiang Province, China.
8. Department of Neurology, Haiyan People's Hospital, Haiyan 314300, Zhejiang Province, China.
9. Department of Neurology, Huzhou Central Hospital, Huzhou 313003, Zhejiang Province, China.
- Publication Type:Journal Article
- MeSH:
Administration, Intravenous;
Brain Ischemia;
drug therapy;
Emergency Medical Services;
Fibrinolytic Agents;
therapeutic use;
Humans;
Prognosis;
Retrospective Studies;
Stroke;
drug therapy;
Thrombolytic Therapy;
statistics & numerical data;
Treatment Outcome
- From:
Journal of Zhejiang University. Medical sciences
2019;48(3):241-246
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the effect of emergency medical service (EMS) on the prognosis of ischemic stroke patients treated with intravenous thrombolysis.
METHODS:Clinical data of 2123 ischemic stroke patients treated with intravenous thrombolysis in 70 hospitals in Zhejiang province were retrospectively analyzed. There were 808 patients sent to the hospital by ambulance (EMS group) and 1315 patients by other transportations (non-EMS group). Good outcome was defined as modified Rankin Scale (mRS) ≤ 2 at 3-month. The onset to needle time (ONT), onset to door time (ODT), door to needle time (DNT) and outcome were compared between EMS group and non-EMS group. Binary logistic regression was used to explore the influencing factors for the outcome at 3-month.
RESULTS:Compared with the non-EMS group, patients in the EMS group were older, with higher baseline National Institute of Health Sroke Scale (NIHSS) score, and had a higher proportion of atrial fibrillation (all <0.05), but there were no significant differences in ONT, ODT and DNT between two groups (all >0.05). Binary logistic regression showed that EMS was not independently associated with good outcome (=0.856, 95%:0.664-1.103, >0.05).
CONCLUSIONS:EMS had not improve the outcome of patients receiving intravenous thrombolysis in Zhejiang province.