Advances in serum biomarkers for early diagnosis of gastric cancer.
- Author:
Yunzhu ZHANG
1
;
Chunpeng ZHU
1
;
Xinliang LU
1
Author Information
1. Department of Gastroenterology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
- Publication Type:Journal Article
- MeSH:
Biomarkers, Tumor;
blood;
Early Detection of Cancer;
trends;
Humans;
Sensitivity and Specificity;
Stomach Neoplasms;
blood;
diagnosis
- From:
Journal of Zhejiang University. Medical sciences
2019;48(3):326-333
- CountryChina
- Language:Chinese
-
Abstract:
Early diagnosis is the key to improve the prognosis of gastric cancer. How to screen out high-risk subjects of gastric cancer in population is a hot spot. Serum-based early detection of gastric cancer is suitable for high-risk population screening, which is more convenient and safer. This article reviews the diagnostic value of serum biomarkers for gastric cancer, including serum DNA methylation, various RNAs, pepsinogen, gastrin, osteopontin, MG7-Ag and CA724. Until now, there is still lack of ideal biomarkers for gastric cancer, and searching for specific RNAs may be promising for early diagnosis and screening of gastric cancer.
