Correlations between the Maximum Standard Uptake Value of Positron Emission Tomography/Computed Tomography and Laboratory Parameters before and after Treatment in Patients with Lymphoma.
- Author:
Edip UCAR
1
;
Hulya YALCIN
2
;
Gamze Hande KAVVASOGLU
1
;
Gul ILHAN
1
Author Information
- Publication Type:Journal Article
- Keywords: Albumin; C-reactive Protein; Erythrocyte Sedimentation Rate; Lactate Dehydrogenase; Lymphoma; Maximum Standard Uptake Value; Positron Emission Tomography/Computed Tomography; White Blood Cell Count
- MeSH: Blood Sedimentation; C-Reactive Protein; analysis; Fluorodeoxyglucose F18; Humans; L-Lactate Dehydrogenase; analysis; Lymphoma; diagnostic imaging; Multimodal Imaging; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Retrospective Studies
- From: Chinese Medical Journal 2018;131(15):1776-1779
- CountryChina
- Language:English
-
Abstract:
Background:After the first examination of patients with lymphoma diagnosis, important laboratory tests such as complete blood count; albumin, kidney and liver function tests; uric acid; β2-microglobulin; C-reactive protein (CRP); erythrocyte sedimentation rate (ESR); and lactate dehydrogenase (LDH) examinations are recommended. In this study, our aim was to find the relationship between laboratory parameters and the maximum standard uptake value (SUV) of positron emission tomography/computed tomography (PET/CT) in patients with lymphoma at the diagnosis and after treatment.
Methods:Thirty-four lymphoma patients treated at Mustafa Kemal University Internal Medicine Clinic between 2014 and 2017 were included in this retrospective study. Results of CRP, ESR, LDH, albumin, and white blood cell (WBC) count were recorded before each PET scan test, and each parameter was analyzed for correlation with SUVmeasurements.
Results:Spearman's correlation test showed that the after-treatment SUVvalues were significantly correlated with the after-treatment LDH, ESR, and CRP values (for LDH, ESR, and CRP, R: 0.453, 0.426, and 0.351; P = 0.007, 0.012, and 0.042, respectively). On the other hand, albumin and WBC count did not show a significant correlation with the after-treatment SUVvalues (all P > 0.05).
Conclusions:CRP, ESR, and LDH values may also be good predictors in patients for whom PET/CT imaging cannot be performed.
