Influence of pre-pregnancy parental body mass index, maternal weight gain during pregnancy, and their interaction on neonatal birth weight.
- Author:
Xiao-Wei SHI
1
;
Jie YUE
;
Min LYU
;
Li WANG
;
E BAI
;
Li-Jun TIE
Author Information
1. Department of Pediatrics, First Hospital of Xi'an Jiaotong University, Xi'an 710061, China. xwshi2010@163.com.
- Publication Type:Journal Article
- MeSH:
Birth Weight;
Body Mass Index;
Female;
Gestational Weight Gain;
Humans;
Infant, Newborn;
Pregnancy;
Pregnancy Complications;
Risk Factors;
Weight Gain
- From:
Chinese Journal of Contemporary Pediatrics
2019;21(8):783-788
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the influence of pre-pregnancy parental body mass index (BMI), maternal weight gain during pregnancy, and their interaction on neonatal birth weight.
METHODS:A total of 1 127 pregnant women who underwent regular prenatal examinations and full-term singleton delivery in the First Hospital of Xi'an Jiaotong University from January 2017 to October 2018 were enrolled. The data on their pre-pregnancy BMI, maternal weight gain during pregnancy, pre-pregnancy BMI of the husband, and neonatal birth weight were collected. The interaction between pre-pregnancy parental BMI and maternal weight gain during pregnancy was analyzed, and their correlation with neonatal birth weight was analyzed.
RESULTS:Among the 1 127 full-term neonates, the detection rates of low birth weight neonates and macrosomia were 2.22% (25/1 127) and 3.82% (43/1 127) respectively. There were significant differences in pre-pregnancy parental BMI and maternal weight gain during pregnancy among the low birth weight, normal birth weight, and macrosomia groups (P<0.05). Neonatal birth weight was positively correlated with pre-pregnancy parental BMI and maternal weight gain during pregnancy (r=0.097-0.322, P<0.05). Low maternal weight before pregnancy increased the risk of low birth weight (RR=4.17, 95%CI: 1.86-9.38), and maternal overweight/obesity before pregnancy (RR=3.59, 95%CI: 1.93-6.67) and excessive weight gain during pregnancy (RR=3.21, 95%CI: 1.39-7.37) increased the risk of macrosomia. No interaction between pre-pregnancy maternal BMI and maternal weight gain during pregnancy was observed.
CONCLUSIONS:Pre-pregnancy parental BMI and maternal weight gain during pregnancy are related to neonatal birth weight, and there is no interaction between pre-pregnancy maternal BMI and maternal weight gain during pregnancy.
