Recurrent skin blisters for more than 7 months in a girl aged 15 months.
- Author:
Ke-Yao LI
1
;
Jian-Ping TANG
;
Xiao-Ting LIANG
;
Zhou-Ying ZHAO
;
Shu-Zhen YUE
Author Information
1. Department of Dermatology, Hunan Children's Hospital, Changsha 410007, China. jpingtang@126.com.
- Publication Type:Case Reports
- MeSH:
Blister;
Female;
Humans;
Infant;
Mast Cells;
Skin
- From:
Chinese Journal of Contemporary Pediatrics
2019;21(9):919-923
- CountryChina
- Language:Chinese
-
Abstract:
A girl, aged 15 months, attended the hospital due to recurrent skin erythema, blisters, and desquamation for more than 7 months. Giemsa staining and immunohistochemical staining showed mast cell infiltration and degranulation. Hematoxylin staining showed spinous layer edema and blister formation under the epidermis, with a large amount of serous fluid and a small number of inflammatory cells in the blister. Marked edema was observed in the dermis, with diffused mononuclear cell infiltration. The girl was diagnosed with mastocytosis. Mastocytosis should be considered for children with recurrent skin erythema and blisters.
