Application of metabolomics in neonatal clinical practice.
- Author:
Qiu-Tong LIU
1
;
Xiao-Yun ZHONG
Author Information
1. Department of Neonatology, Chongqing Health Center for Children and Women, Chongqing 400000, China. 13883519380@163.com.
- Publication Type:Journal Article
- MeSH:
Humans;
Infant, Newborn;
Metabolic Networks and Pathways;
Metabolomics
- From:
Chinese Journal of Contemporary Pediatrics
2019;21(9):942-948
- CountryChina
- Language:Chinese
-
Abstract:
Metabolomics is an emerging and popular subject in the post-genome era, and a large number of studies have been noted on the application of metabolomics in health evaluation, growth and development evaluation, disease diagnosis, and therapeutic efficacy evaluation. As a special period of life, the neonatal period is characterized by rapid cell renewing, consumption of a lot of energy and materials, and changes in metabolic pathways, all of which affect the level of metabolites. However, there is still no reference standard for metabolic level and profile in neonates. This article reviews the current status of metabolic research on neonatal growth and development and common diseases and related clinical application of metabolomics, so as to provide new ideas for nutrition guidance and evaluation, selection of therapeutic regimens, and new drug research in neonates.
