Diffuse alveolar hemorrhage in children.
- Author:
Ting JIANG
1
;
Qu-Bei LI
Author Information
1. Respiratory Center, Children's Hospital of Chongqing Medical University, Chongqing 400014, China. liqubei@126.com.
- Publication Type:Journal Article
- MeSH:
Antibodies, Antineutrophil Cytoplasmic;
Child;
Hemorrhage;
Humans;
Lung Diseases;
Pulmonary Alveoli;
Vasculitis
- From:
Chinese Journal of Contemporary Pediatrics
2019;21(9):949-954
- CountryChina
- Language:Chinese
-
Abstract:
Diffuse alveolar hemorrhage (DAH) is a clinical syndrome with major clinical manifestations of hemoptysis, anemia, and diffuse infiltration in the lung. DAH has a high mortality rate in the acute stage and is a life-threatening emergency in clinical practice. Compared with adult DHA, childhood DHA tends to have a specific spectrum of underlying diseases. It has long been believed that idiopathic pulmonary hemosiderosis (IPH) is the main cause of childhood DAH; however, with the increase in reports of childhood DAH cases, the etiology spectrum of childhood DAH is expanding. The treatment and prognosis of DAH with different etiologies are different. This review article gives a general outline of childhood DAH, with focuses on DAH caused by IPH, systemic lupus erythematosus, anti-neutrophil cytoplasmic antibody-related vasculitis, COPA syndrome, or IgA vasculitis.
