Alcohol consumption analysis among patients with liver disease in China.
10.1097/CM9.0000000000000067
- Author:
Yan-Di XIE
1
;
Chang-Qing ZHAO
2
;
Jiu-Ping WANG
3
;
Chang-Sheng CHENG
4
;
Jun-Ying ZHOU
5
;
Ying ZHANG
6
;
Hong XIA
7
;
Lai WEI
1
Author Information
1. Peking University People's Hospital, Peking University Hepatology Institute, Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases, Beijing 100044, China.
2. Department of Liver Cirrhosis, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China.
3. Department of Infectious Disease, Xijing Hospital, the First Affiliated Hospital of the Air Force Military Medical University, Xi'an, Shaanxi 710032, China.
4. Department of Hepatology, Guidong People's Hospital of Guangxi Zhuang Autonomous Region, Wuzhou, Guangxi 543001, China.
5. Department of Infectious Disease, the Third Hospital of Hebei Medical University, Shijiazhuang, Hebei 050051, China.
6. Sixth Department of Liver Disease, Dalian Sixth People's Hospital, Dalian Medical University, Dalian, Liaoning 116001, China.
7. Department of Infectious Disease, the Dazu District People's Hospital of Chongqing, Chongqing 402360, China.
- Publication Type:Journal Article
- MeSH:
Adult;
Aged;
Alcohol Drinking;
adverse effects;
Alcoholism;
etiology;
Cross-Sectional Studies;
Female;
Humans;
Liver Diseases;
etiology;
Male;
Middle Aged;
Smoking;
adverse effects
- From:
Chinese Medical Journal
2019;132(4):420-430
- CountryChina
- Language:English
-
Abstract:
BACKGROUND:Alcohol consumption has been observed to be a contributing factor in liver damage. However, very few studies have tried to decipher the correlation between patients with liver disease and alcohol consumption. Therefore, this study was planned to determine the prevalence of alcohol consumption among patients with liver disease, and to evaluate the risk factors, liver diseases, and chronic medical conditions associated with alcohol drinking.
METHODS:A cross-sectional study was conducted among patients with liver disease in 30 provinces, autonomous regions, and municipalities across China. All participants answered the questionnaire, which led to the calculation of Alcohol Use Disorders Inventory Test (AUDIT) score for each patient. Based on this score, low-risk drinkers, hazardous drinkers, and harmful drinkers were defined as having AUDIT score of <8, between 8 and 15, and ≥16, respectively.
RESULTS:A total of 1489 participants completed the questionnaire. Based on this information, 900 (60.44%) participants were classified as alcohol drinkers. Among these, 8.66% were ex-drinkers, 22.10% were low-risk drinkers, 17.13% were hazardous drinkers, and 12.56% were harmful drinkers. Further investigation of the association between alcohol consumption and other baseline characteristics of patients with liver disease revealed that usually men <40 years old, participants having higher family annual income, having college degree or higher education, living alone, having higher body mass index (BMI), current smokers, and ex-smokers had significant association with higher risk of alcohol consumption. In addition, among the 18.07% of the participants with cirrhosis, it was observed that risk of cirrhosis increased with higher alcohol consumption. Furthermore, harmful drinkers showed greater odds of hypertension and heart diseases, while hazardous drinkers and harmful drinkers, both had greater odds of hyperlipidemia.
CONCLUSIONS:Overall our analyses indicated that among the patients with liver disease in China, there was high rate of alcohol consumption and dependence. Alcohol consumption usually associated with men <40 years old, higher family income, education level, living alone, high BMI, and smoking. Increased alcohol consumption not only increased the risk of cirrhosis, but also enhanced the risk of hypertension, heart diseases, and hyperlipidemia.
