Clinical efficacy of Bushen Huoxue Anshen therapy in treating perimenopausal sleep disorder with kidney deficiency and blood stasis.
10.19540/j.cnki.cjcmm.20181225.002
- Author:
Kun MA
1
;
Yan-Xia CHEN
1
;
Mei-Ling DONG
2
Author Information
1. Xiyuan Hospital,China Academy of Chinese Medical Sciences Beijing 100091,China.
2. Traditional Chinese Medicine Hospital of Huairou District Beijing 101400,China.
- Publication Type:Journal Article
- Keywords:
Bushen Huoxue Anshen;
Chinese medicine;
acupuncture;
perimenopauseal sleep disorders
- MeSH:
Acupuncture Therapy;
Drugs, Chinese Herbal;
Humans;
Perimenopause;
Sleep Wake Disorders;
therapy;
Treatment Outcome
- From:
China Journal of Chinese Materia Medica
2019;44(6):1069-1074
- CountryChina
- Language:Chinese
-
Abstract:
The efficacy and safety of traditional Chinese medicine and acupuncture in the treatment of kidney-deficiency and bloodstasis perimenopausal sleep disorders were evaluated. A total of 67 subjects who completed the study were randomly divided into two groups. The traditional Chinese medicine group was orally given Bushen Huoxue Anshen Fang,and the acupuncture group was given acupuncture treatment. Both groups were treated for three consecutive courses of treatment,with a course of treatment of 30 days. The changes of PSQI score,improved Kupperman score,TCM syndromes,serum sex hormone,coagulation,routine blood and urine,liver and kidney function and electrocardiogram were observed before and after treatment. After treatment,the total effective rates of Chinese medicine group and acupuncture group were similar or respectively 91. 43% and 87. 50%. The scores of PSQI,improved Kupperman and TCM syndromes in both groups decreased significantly( P<0. 05). The effect of improving Kupperman score in TCM group was better than that in acupuncture group( P< 0. 01). The effect of improving PSQI and TCM syndromes was similar to that in acupuncture group. The levels of serum FSH and LH were decreased in both groups( P<0. 05),but with no significant difference between the two groups; the level of serum E2 was increased in both groups,but with no significant difference. Compared with before treatment,PT was increased in traditional Chinese medicine group( P<0. 05),but with no significant difference in APTT,TT and FIB before and after treatment; PT and TT were prolonged in acupuncture group( P<0. 05),but with no significant difference in APTT and FIB before and after treatment. The effect of improving PT and TT in the acupuncture group was better than that in the traditional Chinese medicine group( P<0. 05). The results showed that TCM and acupuncture had similar therapeutic effects on perimenopausal sleep disorder of kidney deficiency and blood stasis type,and were safe and reliable. The mechanism was related to the improvement of serum FSH and E2 levels.
