Bushen Huoxue herbal medicine in subfertile women with polycystic ovary syndrome: a Meta-analysis.
10.19540/j.cnki.cjcmm.2019.0021
- Author:
Bo-Chao YUAN
1
;
Kun MA
1
;
Chen-Hui ZHANG
1
;
Yuan YUAN
1
Author Information
1. Xiyuan Hospital,China Academy of Chinese Medicine Sciences Beijing 100091,China.
- Publication Type:Journal Article
- Keywords:
Bushen Huoxue;
Meta-analysis;
infertility;
polycystic ovary syndrome
- MeSH:
Drugs, Chinese Herbal;
Female;
Herbal Medicine;
Humans;
Infertility, Female;
Polycystic Ovary Syndrome;
Pregnancy
- From:
China Journal of Chinese Materia Medica
2019;44(6):1080-1086
- CountryChina
- Language:Chinese
-
Abstract:
Meta-analysis of randomized controlled trials( RCTs) was conducted to clarify the effect of Bushen Huoxue herbal medicine in subfertile women with polycystic ovary syndrome. Databases including CNKI,Wan Fang,VIP,Sino Med,PubMed,EMbase,the Cochrane Library were searched until September,2018. Two reviewers independently assessed study eligibility,extracted data,and evaluated the risk of bias for included trials. Meta-analysis used Review Manager 5. 3 software. Seven RCTs( n = 634) were included.RESULTS: of Meta-analysis indicated that,Bushen Huoxue herbal medicine had advantages on increasing pregnancy rate,lowering LH,T and INS. Bushen Huoxue herbal medicine were not clear on increasing ovulation rate,increasing FSH. No serious adverse reaction appearing from Bushen Huoxue herbal medicine was reported in the including researches. The current Meta-analysis showed a promising effect of Bushen Huoxue herbal medicine in subfertile women with polycystic ovary syndrome,but the quality of current evidence was low and possible publication bias.
