A Case of Hyperimmunoglobulinemia E Syndrome.
- Author:
Seung Hyun MOON
;
Dae Hun SUH
;
Kyu Han KIM
;
Kyoung Chan PARK
;
Jai Il YOUN
- Publication Type:Case Report
- MeSH:
Abscess;
Chemotaxis;
Dermatitis;
Dermatology;
Drainage;
Female;
Humans;
Hypergammaglobulinemia*;
Immunoglobulin E;
Infant;
Job Syndrome*;
Korea;
Methicillin-Resistant Staphylococcus aureus;
Neutrophils;
Skin;
Staphylococcal Infections;
Staphylococcus;
Steroids
- From:Korean Journal of Dermatology
1998;36(3):482-486
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The hyperimmunoglobulinemia E (Jobs) syndrome (HIES) is characterized by marked elevated levels of IgE, recurrent cutaneous and systemic staphylococcal infections, atopic-like dermatitis, and defective neutrophil chemotaxis. Three cases of HIES have been reported in Korea, but not in the dermatology literature. We report a case of HIES with cutaneous infections and MRSA (methicillin-resistant Staphylococcus aureus). A 15-month-old girl presented with intractable pruritic excoriated papular pustular skin lesions and multiple subcutaneous abscesses. Surgical drainage of the abscesses and a course of antibiotic treatment in addition to topical steroids for about 7 weeks resulted in a remarkable improvement.
