Solitary Congenital Indeterminate Cell Histiocytoma.
- Author:
Kyoung Ae JANG
;
Eui Chang CHUNG
;
Jee Ho CHOI
;
Kyung Jeh SUNG
;
Kee Chan MOON
;
Jai Kyoung KOH
- Publication Type:Original Article
- MeSH:
Dermatology;
Dermis;
Epidermis;
Forehead;
Histiocytoma*;
Humans;
Infant;
Kidney;
Langerhans Cells;
Male;
S100 Proteins;
Skin
- From:Korean Journal of Dermatology
1998;36(3):498-501
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Indeterminate cell proliferations are rarely described in dermatology literature. Indeterminate cells are characterized by positivity for S-100 protein and CD-la, but are distinguished from Langerhans cells by the absence of Birbeck granules. We present a case of congenital indeterminate cell histiocytoma in a 6-day-old male infant. A Skin examination revealed a solitary, erythematous, 6*6cm, superficially crusted, dome shaped papule on his forehead. A Histopathologic examination showed a dense cellular infiltrate in the dermis, below the atrophic epidermis. Frequently, the nucleus demonstrated a single cleft or crease like the shape of a kidney. These cells showed positivity for S-100 protein. Birbeck granules were not found on electron microscopic examination.