Simulation of the relationship between magnetic medium parameters and heating temperature in magnetic fluid hyperthermia.
10.7507/1001-5515.201806014
- Author:
Yingjiao QU
1
;
Mai LU
2
;
Xi LIU
1
;
Yanping LIN
1
Author Information
1. Key Laboratory of Optoelectronic Technology and Intelligent Control of Ministry of Education, Lanzhou Jiaotong University, Lanzhou 730070, P.R.China.
2. Key Laboratory of Optoelectronic Technology and Intelligent Control of Ministry of Education, Lanzhou Jiaotong University, Lanzhou 730070, P.R.China.mai.lu@hotmail.com.
- Publication Type:Journal Article
- Keywords:
finite element analysis;
magnetic fluid hyperthermia;
magnetic medium;
tumor
- MeSH:
Animals;
Hot Temperature;
Hyperthermia, Induced;
Magnetics;
Neoplasms;
therapy;
Rats
- From:
Journal of Biomedical Engineering
2019;36(2):206-212
- CountryChina
- Language:Chinese
-
Abstract:
In this paper, we established magnetic fluid hyperthermia (MFH) model for rat tumor using the finite element software COMSOL based on the linear response theory. By analyzing four kinds of magnetic medium within relaxation mechanism, such as Fe O 、FeCo、fccFePt and L1 FePt, we studied the influence of the change of magnetic medium radius on dissipation power and temperature field, respectively. At the same time, the optimization method for the parameters of several magnetic medium is proposed, and the applications of four kinds of magnetic medium are given as well. By increasing the dissipation power of the magnetic medium as much as possible, the dose of magnetic medium used in the treatment can be reduced, meanwhile, the adverse effects on health tissue surrounding the tumor will be minimized. The conclusions of this paper can provide reference for magnetic medium preparation applied to MFH.
