An study of ultrasonic monitoring imaging of microwave ablation based on Nakagami statistic parameter.
10.7507/1001-5515.201810031
- Author:
Shan WU
1
;
Shaoqiang SHANG
1
;
Xuewei WANG
1
;
Mingxi WAN
1
;
Siyuan ZHANG
2
Author Information
1. Department of Biomedical Engineering, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P.R. China.
2. Department of Biomedical Engineering, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P.R. China.xjtusyzhang@mail.xjtu.edu.cn.
- Publication Type:Journal Article
- Keywords:
Nakagami;
microwave ablation;
monitor;
ultrasound imaging
- MeSH:
Animals;
Kidney;
diagnostic imaging;
Liver;
diagnostic imaging;
Microwaves;
Radio Waves;
Radiofrequency Ablation;
Swine;
Ultrasonography
- From:
Journal of Biomedical Engineering
2019;36(3):371-378
- CountryChina
- Language:Chinese
-
Abstract:
This paper explored the feasibility of using ultrasonic Nakagami statistic parameter imaging to evaluate the thermal lesion induced by microwave ablation (MWA) in porcine models. In this paper, thermal lesions were induced in livers and kidneys in 5 swines using a clinical MWA system. During this treatment progress, ultrasonic radiofrequency (RF) data were collected. The dynamic changes of Nakagami parameter in the thermal lesion were calculated, and the ultrasonic B-mode images and Nakagami images were reconstructed simultaneously. The contrast-to-noise ratio (CNR) between the thermal lesion and the surrounding normal tissue was calculated over the MWA procedure. After MWA, a bright hyperechoic region appeared in the ultrasonic Nakagami image as an indicator of the thermal lesion and this bright spot enlarged with lesion development during MWA exposure. The mean value of Nakagami parameter in the liver and kidney increased from 0.78 and 0.79 before treatment to 0.91 and 0.92 after treatment, respectively. During MWA exposure, the mean values of CNR calculated from the Nakagami parameter increased from 0.49 to 1.13 in the porcine liver and increased from 0.51 to 0.85 in the kidney, which were both higher than those calculated from the B-mode images. This study on porcine models suggested that the ultrasonic Nakagami imaging may provide an alternative modality for monitoring MWA treatment.
