Progress on numerical simulation of the deposition of inhaled particles in human pulmonary acinus region.
10.7507/1001-5515.201808001
- Author:
Penghui LI
1
;
Rong LI
2
;
Yang QIAO
1
;
Xinxi XU
1
Author Information
1. Institute of Medical Support Technology, Academe of System Engineering, Academy of Military Sciences, Tianjin 300161, P.R.China.
2. Department of Military Preventive Medicine, Logistics University of Chinese People's Armed Police Force, Tianjin 300309, P.R.China.
- Publication Type:Journal Article
- Keywords:
affecting factors;
deposition of inhaled particles;
human pulmonary acinus;
numerical simulation
- MeSH:
Aerosols;
Computer Simulation;
Humans;
Lung;
physiology;
Models, Biological;
Particle Size;
Pulmonary Alveoli;
physiology
- From:
Journal of Biomedical Engineering
2019;36(3):499-503
- CountryChina
- Language:Chinese
-
Abstract:
The inhalation and deposition of particles in human pulmonary acinus region can cause lung diseases. Numerical simulation of the deposition of inhaled particles in the pulmonary acinus region has offered an effective gateway to the prevention and clinical treatment of these diseases. Based on some important affecting factors such as pulmonary acinar models, model motion, breathing patterns, particulate characteristics, lung diseases and ages, the present research results of numerical simulation in human pulmonary acinus region were summarized and analyzed, and the future development directions were put forward in this paper, providing new insights into the further research and application of the numerical simulation in the pulmonary acinus region.
