Research progress on osteochondral tissue engineering.
10.7507/1001-5515.201810001
- Author:
Weiwei LAN
1
;
Weiyi CHEN
2
,
3
;
Di HUANG
2
,
3
Author Information
1. Department of Biomedical Engineering, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, P.R.China.
2. Department of Biomedical Engineering, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, P.R.China
3. Shanxi Key Laboratory of Material Strength & Structural Impact, Institute of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, P.R.China.
- Publication Type:Journal Article
- Keywords:
cytokines;
osteochondral defects;
scaffolds;
seeding cells;
tissue-engineering
- MeSH:
Bone and Bones;
Cartilage, Articular;
Humans;
Tissue Engineering;
Tissue Scaffolds
- From:
Journal of Biomedical Engineering
2019;36(3):504-510
- CountryChina
- Language:Chinese
-
Abstract:
Osteochondral defects is a common clinical joint disease. The complexity of cartilage-bone interface and the poor self-repair capacity of cartilage are both reasons for current relatively limited clinical treatments. The introduction of tissue engineering provides a new treatment method for osteochondral repair. This paper reviews three main elements of cartilage-bone tissue engineering: seed cell source and culture method, cytokines regulation and synergistic effect, and scaffold components and type. We mainly focused on current status quo and future progress of cartilage-bone repair scaffolds. This paper provides some reference for the further development of osteochondral tissue engineering.
