A comparative study of viscoelasticity between normal cornea and keratoconus.
10.7507/1001-5515.201812052
- Author:
Kechao ZHAO
1
;
Xiaojun WANG
2
,
3
;
Weiyi CHEN
1
;
Rui HE
4
;
Xiaona LI
1
;
Yan GAO
4
Author Information
1. School of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, P.R.China.
2. School of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, P.R.China
3. School of Mechanical and Transportation Engineering, Taiyuan University of Technology, Taiyuan 030024, P.R.China.wangxiaojun@tyut.edu.cn.
4. Department of Excimer Laser, Shanxi Eye Hospital, Taiyuan 030002, P.R.China.
- Publication Type:Journal Article
- Keywords:
corneal visualization Scheimpflug technology;
elastic coefficient;
keratoconus;
standard linear solid model;
viscous coefficient
- MeSH:
Area Under Curve;
Cornea;
physiology;
Elasticity;
Humans;
Keratoconus;
pathology;
ROC Curve;
Viscosity
- From:
Journal of Biomedical Engineering
2019;36(4):613-618
- CountryChina
- Language:Chinese
-
Abstract:
Study of the mechanical properties of in vivo corneal materials is an important basis for further study of corneal physiological and pathological phenomena by means of finite element method. In this paper, the elastic coefficient ( ) and viscous coefficient ( ) of normal cornea and keratoconus under pulse pressure are calculated by using standard linear solid model with the data provided by corneal visualization scheimpflug technology. The results showed that there was a significant difference of and between normal cornea and keratoconus cornea ( < 0.05). Receiver operating characteristic curve analysis showed that the area under curve (AUC) for , and their combined indicators were 0.776, 0.895 and 0.948, respectively, which indicated that keratoconus could be predicted by and . The results of this study may provide a reference for the early diagnosis of keratoconus and avoid the occurrence of keratoconus after operation, so it has a certain clinical value.
