Role of Hepatocyte Growth Factor in Wound Repair.
10.3881/j.issn.1000-503X.10246
- Author:
Xiao Ying LIN
1
;
Hong WANG
1
;
Yuan TAN
1
Author Information
1. Department of Burns,the Second Affiliated Hospital,Kunming Medical University, Burn Institute of Yunnan Province,Kunming 650101,China.
- Publication Type:Journal Article
- MeSH:
Cell Movement;
Cell Proliferation;
Hepatocyte Growth Factor;
physiology;
Humans;
Skin Ulcer;
pathology;
Wound Healing
- From:
Acta Academiae Medicinae Sinicae
2018;40(6):822-826
- CountryChina
- Language:Chinese
-
Abstract:
Hepatocyte growth factor (HGF) is a multifunctional cytokine that is related to many diseases. HGF mainly contributes to cell migration,proliferation,and survival and regulates vascular angiogenesis,matrix deposition,and degradation of wound healing. HGF also promotes wound reepithelialization and reduces scar formation. This review article summarizes the role of HGF in wound repair and the relationship between HGF and other growth factors,especially when applied for the clinical treatment of chronic skin ulcers.
