Application of quality constant method in evaluation of Ligusticum chuanxiong pieces.
10.19540/j.cnki.cjcmm.20190522.309
- Author:
Jia SHI
1
;
Li SHEN
2
;
Zhe DENG
3
;
An-Yi ZHAO
1
;
Hui-Fang LYU
2
;
Chang CHEN
1
;
An LIU
1
Author Information
1. Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences Beijing 100700,China.
2. Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences Beijing 100700,China Jiangxi University of Traditional Chinese Medicine Nanchang 330004,China.
3. China National Traditional Chinese Medicine Co.Ltd. Beijing 102600,China.
- Publication Type:Journal Article
- Keywords:
Ligusticum chuanxiong;
ferulic acid;
grades evaluation;
quality constant
- MeSH:
Drugs, Chinese Herbal;
standards;
Ligusticum;
chemistry;
Medicine, Chinese Traditional;
Quality Control
- From:
China Journal of Chinese Materia Medica
2019;44(15):3275-3280
- CountryChina
- Language:Chinese
-
Abstract:
The method of classifying the quality grade of traditional Chinese medicine slices with cross section model quality constant was applied to the grade evaluation of Ligusticum chuanxiong pieces,and a reasonable grade standard of L. chuanxiong pieces was established. The purpose is to classify the 15 batches of L. chuanxiong pieces by combining the advantages of traditional grading with modern quality control indicators. By measuring the natural morphological parameters,processing parameters and the intrinsic content of ferulic acid,an important active ingredient,of the 15 batches of L. chuanxiong pieces collected from different manufacturers and different batches of different medicinal materials markets,we can synthesize the results. The mass constants and percentage mass constants are calculated and analyzed based on the above data. The results showed that the quality constants of 15 batches of L. chuanxiong pieces collected ranged from 0.53-3.00; if the percentage mass constants were more than 80%,50%-80% was second-class pieces,and the rest were third-class pieces,the evaluation results were as follows: the quality constants of first-class L. chuanxiong pieces were more than 2.40,the quality constants of second-class L. chuanxiong pieces should be 1.70-2.40,and the quality constants of third-class L. chuanxiong pieces should be less than 1.70. In this paper,the method of dividing the quality constants of the top blade model into different grades is further applied and practiced,which proves that the method is scientific,reasonable and multi-adaptable. At the same time,it enriches the research data of the grade evaluation of L. chuanxiong pieces,provides a useful reference for the promotion of the grade evaluation of L. chuanxiong pieces,and lays an experimental foundation for the next research of the subject group.
