Effect of Tripterygium Glycosides Tablets in treating rheumatoid arthritis:a systematic review and Meta-analysis.
10.19540/j.cnki.cjcmm.20190305.004
- Author:
Guang-Zhao ZHU
1
;
Xiao-Chen HAN
2
;
Han-Zhou WANG
3
;
Yu-Zheng YANG
3
;
Yang GAO
4
;
Hai-Long WANG
4
Author Information
1. Beijing University of Chinese Medicine Beijing 100029,China.
2. Beijing Fengsheng Hospital of Traditional Chinese Medicine Orthopedics Beijing 100034,China.
3. Guiyang University of Chinese Medicine Guiyang 550025,China.
4. Guang'anmen Hospital,China Academy of Chinese Medical Sciences Beijing 100053,China.
- Publication Type:Journal Article
- Keywords:
Meta-analysis;
Tripterygium Glycosides Tablets;
radiological progression;
rheumatoid arthritis
- MeSH:
Antirheumatic Agents;
pharmacology;
Arthritis, Rheumatoid;
drug therapy;
Glycosides;
pharmacology;
Humans;
Tablets;
Tripterygium;
chemistry
- From:
China Journal of Chinese Materia Medica
2019;44(15):3358-3364
- CountryChina
- Language:Chinese
-
Abstract:
To evaluate the effect of Tripterygium Glycosides Tablets extract in the treatment of rheumatoid arthritis( RA). Clinical trials of treating rheumatoid arthritis with Tripterygium Glycosides Tablets published by Meta-analysis were retrieved from EMbase,PubMed,Clinical Trials,Web of Science,Cochrane Library,CNKI,Wanfang,VIP,CBM and Chi CTR,and comprehensively analyzed. A total of 3 studies were enrolled,the modified Sharp score( m TSS),tender join joint erosions( JE) and joint space narrowing( JSN) of Tripterygium Glycosides Tablets group were significant superior to those of control group,including positive drugs methotrexate( MTX) and salazopyridine( SSZ)( P<0. 01). Tripterygium Glycosides Tablets had an effect in treating RA. Due to the small sample size,this study shall be verified with high-quality,large-sample-size double-blinded RCTs.
