Radiomics for prediction of central lymph node metastasis in the neck in patients with thyroid papillary carcinoma.
10.12122/j.issn.1673-4254.2019.09.15
- Author:
Weizhen WANG
1
;
Yingjia LI
1
Author Information
1. Department of Medical Ultrasonics, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
- Publication Type:Journal Article
- Keywords:
central lymph node metastasis;
papillary thyroid carcinoma;
radiomics
- MeSH:
Carcinoma, Papillary;
diagnostic imaging;
pathology;
Humans;
Image Interpretation, Computer-Assisted;
Lymph Nodes;
Lymphatic Metastasis;
diagnostic imaging;
Neck;
Prospective Studies;
Thyroid Neoplasms;
diagnostic imaging;
pathology;
Ultrasonography
- From:
Journal of Southern Medical University
2019;39(9):1094-1098
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the feasibility of radiomics for predicting lymph node metastasis in the central region of the neck in patients with thyroid papillary carcinoma (PTC).
METHODS:A total of 189 patients with PTC confirmed by thyroid fine needle aspiration biopsy were prospectively enrolled in this study. The cross-sectional and longitudinal ultrasound images and the images of both sections were analyzed for predicting central lymph node metastasis using a radiomics approach with pathological results as the gold standard.
RESULTS:In the 189 patients, the accuracy, sensitivity and specificity of preoperative thyroid ultrasonography for diagnosis of central lymph node metastasis was 69.39%, 64% and 73%, respectively. Based on the ultrasound images of the cross-sections, longitudinal sections and both sections, the accuracy, sensitivity and specificity of radiomics for predicting central lymph node metastasis was 66.06%/68.12%/77.69%, 53%/46%/40%, and 52%/53%/51%, respectively.
CONCLUSIONS:Radiomics with combined analysis of the ultrasound images on the cross-section and longitudinal section images achieves a higher accuracy for predicting central lymph node metastasis than analysis a single section, and its diagnostic accuracy is much higher than that of conventional ultrasound examination.
