Applying the China-PAR Risk Algorithm to Assess 10-year Atherosclerotic Cardiovascular Disease Risk in Populations Receiving Routine Physical Examinations in Eastern China.

Hui Hua LI; Shan HUANG; Xing Zhen LIU; Da Jin ZOU

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Applying the China-PAR Risk Algorithm to Assess 10-year Atherosclerotic Cardiovascular Disease Risk in Populations Receiving Routine Physical Examinations in Eastern China.

Author: Hui Hua LI ¹ ; Shan HUANG ¹ ; Xing Zhen LIU ² ; Da Jin ZOU ³
Author Information

1. Departmemt of Endocrinology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China.
2. Army Convalescence Area, Hangzhou Aeronautical Sanatorium of Chinese Air Force, Hangzhou 310007, Zhejiang, China.
3. Obesity and Diabetes Center of Naval Medical University, Shanghai 200433, China.
Publication Type:Journal Article
Keywords: Cardiovascular disease; Cardiovascular risk score; China-PAR equation; Risk factors
MeSH: Adult; Aged; Algorithms; Atherosclerosis; epidemiology; China; Female; Humans; Male; Middle Aged; Physical Examination; Risk Factors
From: Biomedical and Environmental Sciences 2019;32(2):87-95
CountryChina
Language:English
Abstract: OBJECTIVE:To assess the 10-year Atherosclerotic Cardiovascular Disease (ASCVD) risk score among adults in eastern China using the China-PAR equation which formulated primarily for the Chinese population.
METHODS:Data from 72,129 individuals from 35-74 years old who received routine physical examinations in eastern China were analyzed in this study. The 10-year risk scores were calculated using the China-PAR equation. The chi-square test and logistic regression were then performed to evaluate the association between the selected risk factors and overall CVD risk.
RESULTS:The mean 10-year ASCVD risk scores were 3.82% ± 3.76% in men and 1.30% ± 1.65% in women based on the China-PAR equation. Overall, 20% of men and 3.5% of women were intermediate-risk, and 7.3% of men and 0.3% of women were high-risk. Waist to hip ratio (WHR) [OR = 1.16 (CI 95% = 1.06-1.26)], waist to height ratio (WHtR) [OR = 1.16 (CI 95% = 1.05-1.28)], non-high-density lipoprotein cholesterol (non-HDL-C) [OR = 1.23 (CI 95% = 1.09-1.39)], and total cholesterol (TC)/HDL-C [OR = 1.68 (CI 95% = 1.46-1.94)] were more strongly associated with CVD risk than body-mass index (BMI), waist circumference (WC), and TC alone.
CONCLUSION:Male-specific prevention and treatment strategies for ASCVD are needed in eastern China. In addition, WHR, WHtR, non-HDL-C, and TC/HDL-C which not included in the the China-PAR equation were also independently associated with 10-year ASCVD risk score categories.