Protocol of Jidong Women Health Cohort Study: Rationale, Design, and Baseline Characteristics.

Meng Si Qiu; Xian Wei Wang; Yan Yao; Si Qi GE; Hua Min Liu; Ying Chun Dai; Yong Zhou

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Protocol of Jidong Women Health Cohort Study: Rationale, Design, and Baseline Characteristics.

Author: Meng Si QIU ¹ ; Xian Wei WANG ² ; Yan YAO ³ ; Si Qi GE ^{4
,

5} ; Hua Min LIU ⁶ ; Ying Chun DAI ¹ ; Yong ZHOU ²
Author Information

1. Department of Epidemiology, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou 510515, Guangdong, China.
2. Sanbo Brain Institute, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, China.
3. Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100160, China.
4. Department of Neuroepidemiology, Beijing Neurosurgical Institute
5. Capital Medical University, Beijing 100070, China.
6. School of Public Health, Taishan Medical University, Tai'an 271016, Shandong, China.
Publication Type:Journal Article
Keywords: Cardiovascular disease; Chinese population-based; Menopause; Protocol; Women
MeSH: Adult; Cardiovascular Diseases; epidemiology; China; epidemiology; Cohort Studies; Female; Humans; Menopause; Middle Aged; Research Design; Risk Factors; Women's Health
From: Biomedical and Environmental Sciences 2019;32(2):144-152
CountryChina
Language:English
Abstract: OBJECTIVE:The Jidong Women Health Cohort Study is a prospective cohort study on female-specific characteristics and risks of chronic diseases in Chinese women and focuses on the potential association between menopause and risks of cardiovascular disease (CVD).
METHODS:The study includes 4,179 female participants with an age of older than 18 years from Caofeidian district, Tangshan city, northern China. Baseline information on female-specific characteristics and potential cardiovascular risk factors was collected and all the participants underwent a physical examination with blood samples collected in 2013. To establish a better risk assessment tool of female CVD, updated information from questionnaire investigation, physical examinations and occurrence of outcome events will be collected through a longitudinal follow-up annually up to the year 2024.
RESULTS:At baseline, Mean age of the participants was 42.3 ± 12.8 years. Reproduction occurred in 2,948 participants (70.5%), menopausal transition in 173 (4.3%), and postmenopause in 1,058 (25.3%). The incidence of arterial hypertension, dyslipidemia, and diabetes showed significant difference across different groups stratified by Stage of Reproductive Aging Workshop (STRAW) system (P < 0.05).
CONCLUSION:The Jidong Women Health Cohort Study will contribute to the scientific evidence on association between female-specific characteristics and cardiovascular risks, and will also be helpful to provide a new path for early detection and prevention of CVD.