Periodontal treatment of a Glanzmann's thrombasthenia patient: A case report.
10.5051/jkape.1997.27.3.597
- Author:
Hak Churl LEE
1
;
Soo Boo HAN
;
Woo Sung KIM
;
Hye Ja LEE
Author Information
1. Department of Periodontology, School of Dentistry, Seoul National University, Korea.
- Publication Type:Case Report
- Keywords:
thrombasthenia;
Glanzmann's;
blood platelet disorder;
glycoproteins
- MeSH:
Adult;
Anemia, Iron-Deficiency;
Bleeding Time;
Blood Platelet Disorders;
Blood Platelets;
Chronic Periodontitis;
Diagnosis;
Female;
Gingiva;
Glycoproteins;
Hemorrhage;
Hemostasis;
Humans;
Inflammation;
Mandible;
Maxilla;
Oral Hygiene;
Platelet Count;
Platelet Membrane Glycoproteins;
Root Planing;
Thrombasthenia*;
Tooth
- From:The Journal of the Korean Academy of Periodontology
1997;27(3):597-602
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Glanzmann's thrombasthenia is a qualitative platelet disorder characterized by a deficiency in the platelet membrane glycoproteins IIb/IIIa. It belongs to a group of hereditary platelet disorders typified by normal platelet numbers and a prolonged bleeding time. The severity of bleeding does not correlate with the severity of the platelet glycoprotein IIb/IIIa abnormality. The present case report describes the periodontal treatment of a patient with Glanzmann's thrombasthenia. A 30-year-old female with a history of Glanzmann's thrombasthenia was referred for gingival bleeding on tooth brushing and discomforts in #38 area. The periodontal finding revealed a diagnosis of localized slight adult periodontitis. Root planing and extraction of #38 was performed under 12 pack of platelets transfusion and digital compression was done for hemostasis. The gingival bleeding ceased within a day in maxilla and 2 days later in mandible. 42 pack of platelets was administered for 3 days of post-treatment and for iron-deficiency anemia 3 pack of RBCs was transfused 2 days later. 1 week later the inflammation in gingiva disappeared and gingival stippling appeared. The clinical result we got was good and in such a medically compromised patient it is an ability to maintain a proper oral hygiene that is essential both for oral and systemic health.
