Biomechanical research progress on sex differences of abdominal aortic aneurysm.
10.7507/1001-5515.201803032
- Author:
Ming LIU
1
,
2
;
Yaxing ZHANG
1
,
2
;
Zujie GAO
1
,
2
;
Zhenze WANG
3
;
Yifeng XI
1
,
2
;
Anqiang SUN
1
,
2
;
Xiaoyan DENG
1
,
2
Author Information
1. Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science & Medical Engineering, Beihang University, Beijing 100191, P.R.China
2. Beijing Advanced Innovation Centre for Biomedical Engineering, Beihang University, Beijing 102402, P.R.China.
3. National Research Center for Rehabilitation Technical Aids, Key Laboratory of Human Motion Analysis and Rehabilitation Technology of the Ministry of Civil Affairs, Beijing Key Laboratory of Rehabilitation Technical Aids for Old-Age Disability, Beijing 100176, P.R.China.
- Publication Type:Journal Article
- Keywords:
abdominal aortic aneurysm;
biomechanics;
sex differences
- From:
Journal of Biomedical Engineering
2018;35(6):959-963
- CountryChina
- Language:Chinese
-
Abstract:
The phenomenon of sex differences exists in patients who have abdominal aortic aneurysms (AAA). The occurrence rate of AAA is higher in male, while the rates of rupture and postoperative mortality are higher for female. This phenomenon of sex differences would affect the diagnosis, treatment and postoperative rehabilitation for AAA patients. This article reviewed the recent research status of sex differences on AAA, and explored the phenomenon of sex differences from the aspects of threshold determination, biomechanics and mechanobiology. This review points out that the sex differences on AAA could ascribe to the differences of biomechanical environment and biological properties induced by the vascular size, anatomy structure and structure components of abdominal aortic artery. The comprehensive investigations of the sex differences on AAA could help to optimize the diagnosis, treatment and device design, patient care and rehabilitation strategy of AAA based on sex differences phenomenon.
