Effect of arterial flow on muscle atrophy.
10.7507/1001-5515.201801032
- Author:
Sili HE
1
,
2
;
Wentao JIANG
1
,
3
;
Ruiqi DONG
1
,
2
;
Fei YAN
1
,
2
;
Zhi XU
1
,
2
;
Yubo FAN
4
,
5
Author Information
1. Department of Mechanics & Engineering, College of Architecture and Environment, Sichuan University, Chengdu 610065, P.R.China
2. Sichuan Province Biomechanical Engineering Laboratory, Sichuan University, Chengdu 610065, P.R.China.
3. Sichuan Province Biomechanical Engineering Laboratory, Sichuan University, Chengdu 610065, P.R.China.scubme@aliyun.com.
4. National Research Center for Rehabilitation Technical Aids, Beijing 100176, P.R.China
5. Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, P.R.China.
- Publication Type:Journal Article
- Keywords:
artery;
hemodynamics;
muscle atrophy;
numerical simulation;
residual limb
- From:
Journal of Biomedical Engineering
2019;36(1):68-72
- CountryChina
- Language:Chinese
-
Abstract:
This study analyzed the inherent relation between arterial blood mass flow and muscle atrophy of residual limb to provide some necessary information and theoretical support for the clinical rehabilitation of lower limb amputees. Three-dimensional arterial model reconstruction was performed on both intact side and residual limb of a unilateral transfemoral amputee who is the subject. Then hemodynamic calculation was carried out to comparatively analyze the mass flow state at each arterial outlet of both lower extremities. The muscle atrophy ratio of residual limb was calculated by measuring the cross-sectional area of bilateral muscles. Based on the blood supply relationship, the correlation between arterial blood flow reduction ratio and muscle atrophy ratio was discussed. The results showed that the mass flow of superficial femoral arteries and lateral circumflex femoral arteries severely reduced. Meanwhile rectus femoris, vastus lateralis and vastus medialis which were fed by these arteries showed great atrophy too. On the contrary, the mass flow of deep femoral arteries and medial femoral circumflex arteries slightly reduced. Meanwhile gracilis, adductor longus, long head of biceps which were fed by these arteries showed mild atrophy too. These results indicated that there might be a positive and promotion correlation between the muscle atrophy ratio and the blood mass flow reduction ratio of residual limb during rehabilitation.
