Exploration of objective quality evaluation parameter of Alismatis Rhizoma decoction pieces.
10.19540/j.cnki.cjcmm.20190326.301
- Author:
De-Wen LIU
1
;
Zhe DENG
2
;
Jia SHI
3
;
Meng-Jiao JIAO
3
;
Yan TONG
3
;
Jin-Yu WANG
3
;
Jin-Tang CHENG
3
;
Sha CHEN
3
;
Chang CHEN
3
;
Jun ZHANG
3
;
Li SHEN
1
;
Huan YU
4
;
Zheng-Hong PAN
5
;
Qian-Feng GONG
4
;
An LIU
3
Author Information
1. School of Pharmacy,Jiangxi University of Traditional Chinese Medicine Nanchang 330004,China Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences Beijing 100700,China.
2. Institute of Traditional Chinese Medicine,China National Traditional & Herbal Medicine Co.,Ltd. Beijing 102600,China.
3. Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences Beijing 100700,China.
4. School of Pharmacy,Jiangxi University of Traditional Chinese Medicine Nanchang 330004,China.
5. Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization,Guangxi Institute of Botany,Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences Guilin 541006,China.
- Publication Type:Journal Article
- Keywords:
Alismatis Rhizoma;
alisol B 23-acetate;
decoction pieces;
objective indexes;
quality constant;
shape coefficient
- MeSH:
Alisma;
chemistry;
Chromatography, High Pressure Liquid;
Drugs, Chinese Herbal;
standards;
Quality Control;
Rhizome;
chemistry
- From:
China Journal of Chinese Materia Medica
2019;44(9):1729-1733
- CountryChina
- Language:Chinese
-
Abstract:
To establish a quality constant evaluation system of Alismatis Rhizoma decoction pieces,in order to provide reference for regulating the market circulation of this decoction pieces. A total of 18 batches of Alismatis Rhizoma decoction pieces were collected from different pharmaceutical factories,and the morphological parameters of each sample were tested. The content of alisol B 23-acetate in Alismatis Rhizoma decoction pieces was determined by HPLC in the 2015 edition of Chinese Pharmacopoeia,and the parameters such as quality constant and relative quality constant were calculated. The quality constant range of 18 batches of Alismatis Rhizoma decoction pieces was 0. 390-2. 076. If 18 batches of Alismatis Rhizoma decoction pieces were divided into 3 grades,taking 80% of the maximum quality constant as first grade,50% to 80% as second grade,and the rest as third grade,then the quality constant of firstgrade samples was ≥1. 66,the quality constant of second-grade samples was ≥1. 04 and <1. 66,and the quality constant of third-grade samples was <1. 04. The established quality constant evaluation method is objective and feasible,which can be used to classify the grade of Alismatis Rhizoma decoction pieces and provide a reference method to control the quality of this decoction pieces.
