High quality and superior effect of Dachuanxiong Formula based on quality constant grading evaluation technology of Chinese medicine pieces.
10.19540/j.cnki.cjcmm.20190221.007
- Author:
Jia SHI
1
;
Meng-Jiao JIAO
1
;
Zhe DENG
2
;
Li SHEN
1
;
Chang CHEN
1
;
Jun ZHANG
1
;
An LIU
1
Author Information
1. Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences Beijing 100700,China.
2. Institute of Traditional Chinese Medicine,China National Traditional & Herbal Medicine Co.,Ltd. Beijing 102600,China.
- Publication Type:Journal Article
- Keywords:
Dachuanxiong Formula;
Gastrodia elata;
Ligusticum chuanxiong;
grading;
quality constant
- MeSH:
Drugs, Chinese Herbal;
standards;
Gastrodia;
chemistry;
Glycyrrhiza;
chemistry;
Ligusticum;
chemistry;
Medicine, Chinese Traditional;
Plant Roots;
chemistry;
Quality Control;
Rhizome;
chemistry
- From:
China Journal of Chinese Materia Medica
2019;44(9):1755-1759
- CountryChina
- Language:Chinese
-
Abstract:
Quality constant is a kind of grading evaluation method of traditional Chinese medicine pieces based on the combination of traditional knowledge and modern quality control. This method has been successfully applied in the grading evaluation of Glycyrrizae Radix et Rhizome pieces and traditional Chinese medicine pieces,and with a positive influence in the industry. With Dachuanxiong Formula for example,different grades of Ligusticum chuanxiong and Gastrodia elata pieces formed high-quality,moderate and qualified Dachuanxiong Formula on the basis of the grading evaluation of the pieces,and the pharmacodynamics method was used to evaluate its efficacy. The results showed that the maximum vascular diastolic rates of Dachuanxiong Formula in the three grades were( 80. 3±5. 2) %,( 67. 0±6. 1) %and( 60. 3±6. 5) %,and the strength of pharmacodynamics was positively correlated with the grade of L. chuanxiong and G. elata pieces.The quality constant technique can objectively and quantitatively classify single decoctions,and has important correlations and prompts for the efficacy of traditional Chinese medicine prescriptions composed of these pieces,with important significance in promoting hierarchical management of the industry,implementing better price for high quality and defining high quality and superior effect.
