Neurological Abnormality Could be the First and Only Symptom of Familial Hemophagocytic Lymphohistiocytosis: Report of Two Families.

Author: Yun-Ze ZHAO ^{1
,

2
,

3
,

4} ; Hua CHENG ⁵ ; Chang-Hong DING ⁶ ; Hong-Hao MA ^{1
,

2
,

3
,

4} ; Tong-Li HAN ⁶ ; Jiu-Wei LI ⁶ ; Dong WANG ^{1
,

2
,

3
,

4} ; Zhi-Gang LI ^{1
,

2
,

3
,

4} ; Tian-You WANG ^{1
,

2
,

3
,

4} ; Rui ZHANG ^{1
,

2
,

3
,

4}
Author Information

1. Beijing Key Laboratory of Pediatric Hematology Oncology
2. National Key Discipline of Pediatrics (Capital Medical University)
3. Key Laboratory of Major Diseases in Children, Ministry of Education
4. Hematology Oncology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.
5. Department of Radiology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.
6. Department of Neurology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.
Publication Type:Case Reports
MeSH: Central Nervous System Diseases; etiology; Child; Female; Humans; Infant; Lymphohistiocytosis, Hemophagocytic; complications; diagnosis; genetics; Magnetic Resonance Imaging; Male; Mutation; Perforin; genetics
From: Chinese Medical Journal 2018;131(24):3004-3006
CountryChina
Language:English