Invasive mucinous adenocarcinoma with lepidic-predominant pattern coexisted with tuberculosis: a case report.
10.1007/s11684-017-0545-4
- Author:
Xinxin XU
1
;
Yinshi GUO
2
;
Qiuying LI
3
;
Ling YANG
4
;
Jianqiang KANG
1
Author Information
1. Department of Geriatrics, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China.
2. Allergy Department, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200001, China.
3. Department of Interventional Radiology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, China.
4. Department of Geriatrics, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China. yanglingjoy@hotmail.com.
- Publication Type:Case Reports
- Keywords:
invasive mucinous adenocarcinoma;
lepidic-predominant;
tuberculosis
- MeSH:
Adenocarcinoma, Mucinous;
diagnosis;
pathology;
Aged, 80 and over;
Antibiotics, Antitubercular;
therapeutic use;
Disease Progression;
Humans;
Lung Neoplasms;
diagnosis;
pathology;
Male;
Mycobacterium tuberculosis;
isolation & purification;
Positron Emission Tomography Computed Tomography;
Pulmonary Alveoli;
pathology;
Tuberculosis, Pulmonary;
diagnosis;
drug therapy
- From:
Frontiers of Medicine
2018;12(3):330-333
- CountryChina
- Language:English
-
Abstract:
We observed a rare case of invasive mucinous adenocarcinoma (IMA) with a lepidic-predominant pattern accompanied by pulmonary tuberculosis. An 85-year-old man with repeated cough and sputum was admitted to Xinhua Hospital. T-SPOT test result was 212 pg/ml (reference value of negative is < 14 pg/ml), Mycobacterium tuberculosis culture was positive, and tuberculin skin test (PPD) was negative (skin induration < 5 mm). The patient was treated with several courses of antibiotics and anti-tuberculosis treatments. Repeated chest CT scans showed disease progression. Bronchoscopy yielded negative results. PET-CT scans showed negative results. A percutaneous lung biopsy revealed mucin-secreting cells lining the alveolar walls. IMA with a lepidic-predominant pattern was diagnosed after invasiveness was found after experimental treatments. Simultaneous occurrence of pulmonary tuberculosis and lung cancer are common; however, the present case of IMA having a lepidic-predominant pattern and coexisting with active tuberculosis has not been reported yet.
