Radical versus conservative surgical treatment of liver hydatid cysts: a meta-analysis.
10.1007/s11684-017-0559-y
- Author:
Qing PANG
1
;
Hao JIN
1
;
Zhongran MAN
1
;
Yong WANG
1
;
Song YANG
1
;
Zongkuang LI
1
;
Yimin LU
1
;
Huichun LIU
2
;
Lei ZHOU
3
Author Information
1. Department of Hepatobiliary Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, 233000, China.
2. Department of Hepatobiliary Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, 233000, China. liuhcdoctor@126.com.
3. Department of Hepatobiliary Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, 233000, China. zidane20082003@163.com.
- Publication Type:Letter
- Keywords:
complications;
conservative surgery;
liver hydatid cysts;
meta-analysis;
radical surgery
- MeSH:
Echinococcosis, Hepatic;
mortality;
surgery;
Humans;
Length of Stay;
statistics & numerical data;
Operative Time;
Postoperative Complications;
epidemiology;
Recurrence;
Treatment Outcome
- From:
Frontiers of Medicine
2018;12(3):350-359
- CountryChina
- Language:English
-
Abstract:
To date, the efficacy of radical surgery (RS) versus conservative surgery (CS) for liver hydatid cysts (LHC) remains controversial. This meta-analysis was conducted to compare the two interventions. PubMed, Embase, and Web of Science were searched from their inceptions until June 2016. Meta-analysis was performed using STATA 12.0 software. We identified 19 eligible studies from 10 countries by retrieval. In total, 1853 LHC patients who received RS were compared with 2274 patients treated by CS. The risk of postoperative overall complication, biliary fistula, and recurrence was significantly lower, and operation time was significantly longer in the RS group. However, no statistically significant differences were found in terms of mortality risk and the duration of hospital stay between RS and CS. No significant publication biases were observed in all the above analyses. In conclusion, RS reduces the rates of postoperative complications and recurrence, whereas no trend toward such a reduction in mortality was observed in LHC patients.