Effect of histone acetylation on osteogenic differentiation of periodontal ligament stem cells derived from periodontitis tissue.

Author: Jin SUN ¹ ; Yun LIU ¹ ; Qian QU ¹ ; Juan QU ¹ ; Wei LUO ¹ ; Feng ZHANG ¹ ; Min WU ¹
Author Information

1. Stomatology Health Care Center, Shenzhen Maternity & Child Healthcare Hospital, Southern Medical University, Shenzhen 518048, China.
Publication Type:Journal Article
Keywords: chronic periodontitis; histone acetylation; osteogenic differentiation; periodontal ligament stem cells
MeSH: Acetylation; Cell Differentiation; Cells, Cultured; Histones; metabolism; Osteogenesis; Periodontal Ligament; Stem Cells; physiology
From: West China Journal of Stomatology 2019;37(1):102-105
CountryChina
Language:Chinese
Abstract: Epigenetics is defined as a change in gene expression without the alteration of the genetic sequence. Such a change would be inherited by offspring. Histone acetylation is a type of epigenetics. Existing studies proposed that chronic periodontitis is related to epigenetic modification. In this review, we summarised the influence of chronic periodontitis on periodontal ligament stem cells by histone acetylation.