Effect of histone acetylation on osteogenic differentiation of periodontal ligament stem cells derived from periodontitis tissue.
- Author:
Jin SUN
1
;
Yun LIU
1
;
Qian QU
1
;
Juan QU
1
;
Wei LUO
1
;
Feng ZHANG
1
;
Min WU
1
Author Information
- Publication Type:Journal Article
- Keywords: chronic periodontitis; histone acetylation; osteogenic differentiation; periodontal ligament stem cells
- MeSH: Acetylation; Cell Differentiation; Cells, Cultured; Histones; metabolism; Osteogenesis; Periodontal Ligament; Stem Cells; physiology
- From: West China Journal of Stomatology 2019;37(1):102-105
- CountryChina
- Language:Chinese
- Abstract: Epigenetics is defined as a change in gene expression without the alteration of the genetic sequence. Such a change would be inherited by offspring. Histone acetylation is a type of epigenetics. Existing studies proposed that chronic periodontitis is related to epigenetic modification. In this review, we summarised the influence of chronic periodontitis on periodontal ligament stem cells by histone acetylation.