Bisphosphonate-related osteonecrosis of the jaw complicated with wrist scaphoid osteomyelitis: a case report.

Author: Zhao-Wei SUN ¹ ; Zhi-Yong LI ¹ ; Dan YU ² ; Jie-Ying ZHU ¹ ; Yi-Dian ZHANG ² ; Xin-Mei ZHU ¹
Author Information

1. Dept. of Oral and Maxillofacial Surgery, Stomatology Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.
2. Dept. of Oral and Maxillofacial Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.
Publication Type:Case Reports
Keywords: bisphosphonate; osteonecrosis of the jaw; scaphoid osteomyelitis; zoledronic acid
MeSH: Bisphosphonate-Associated Osteonecrosis of the Jaw; complications; Bone Density Conservation Agents; Diphosphonates; Humans; Osteomyelitis; complications; Wrist; pathology
From: West China Journal of Stomatology 2019;37(2):224-228
CountryChina
Language:Chinese
Abstract: Bisphosphonates can directly inhibit osteoclasts, which may lead to increased bone density, reduced blood flow, and osteonecrosis of the jaw. Bisphosphonate-related osteonecrosis is usually observed in the jaw bone. In this article, we report a patient with bisphosphonate-related osteonecrosis of the jaw (BRONJ) complicated with wrist scaphoid osteomyelitis. Furthermore, we introduce the pathogenesis, treatment, and prevention of BRONJ.