Human mycobiome and diseases.

Author: Xin SHEN ¹ ; Yu-Fei YAO ¹ ; Ji-Yao LI ² ; Yan LI ¹
Author Information

1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
2. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Conservative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Publication Type:Journal Article
Keywords: bacteriome; diseases; hostimmune response; interaction; mycobiome
MeSH: Bacteria; Disease; Female; Fungi; Humans; Microbiota; Mouth; Mycobiome
From: West China Journal of Stomatology 2019;37(3):314-319
CountryChina
Language:Chinese
Abstract: The proportion of mycobiome is less than 1% of human microbiome. However, fungal community plays a key role in human health and diseases. With high-throughput sequencing applications, the structure and composition of mycobiome in the mouth, lung, gut, vagina, and skin have been analyzed, and the role of microbiome in diseases has been investigated. Mycobiome also influences the composition of bacteriome and includes key species that maintain the structure and function of microbial communities. Fungi also influence host immune responses. In this review, we summarized the mycobiome com-position at various sites and different diseases and the interactions between fungi-bacteria and fungi-host.