Research progress on the modification of guided bone regeneration membranes.

Yu-bin Cao; Chang Liu; Wei-lin Pan; Yuan TU; Chun-jie LI; Cheng-ge Hua

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Research progress on the modification of guided bone regeneration membranes.

Author: Yu-Bin CAO ¹ ; Chang LIU ² ; Wei-Lin PAN ² ; Yuan TU ¹ ; Chun-Jie LI ^{3
,

4} ; Cheng-Ge HUA ^{4
,

5}
Author Information

1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Head and Neck Oncology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
2. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
3. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Head and Neck Oncology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
4. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Evidence-based Stomatology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
5. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
Publication Type:Journal Article
Keywords: biological membrane; bone tissue engineering; collagen membrane; guided bone regeneration
MeSH: Bone Regeneration; Collagen; Membranes, Artificial; Osteoblasts; Osteogenesis
From: West China Journal of Stomatology 2019;37(3):325-329
CountryChina
Language:Chinese
Abstract: Guided bone regeneration (GBR) is an important technique to solve bone defect problems. In this technique, GBR barrier membranes play an irreplaceable role. GBR membranes can act as a barrier protecting fibroblasts from bone defects and promote osteoblast adhesion and proliferation, leading to bone regeneration. GBR barrier membranes should be enhanced because of the disadvantages of collagen membranes, which are extensively applied to the field of GBR. Therefore, various efforts have been devoted to modifying the antibacterial and osteogenic properties of GBR barrier membranes and developing novel materials. This article reviews the research advancements on the modification of GBR barrier membranes and discover future directions for the development of GBR barrier membranes to provide a reference for bone tissue engi-neering and repair.