Comparison of Related Factors between Twins in Which Premature of Retinopathy Developed on One Twin.
10.3341/jkos.2016.57.10.1592
- Author:
Jae Wan LIM
1
;
Jae Ho YOO
;
Seung Uk LEE
;
Sang Joon LEE
;
Ki Yup NAM
Author Information
1. Department of Ophthalmology, Kosin University College of Medicine, Busan, Korea. oksnam1231@hanmail.net
- Publication Type:Original Article
- Keywords:
Aspartate aminotransferase;
Platelet;
Retinopathy of prematurity (ROP);
Twin
- MeSH:
Apgar Score;
Aspartate Aminotransferases;
Blood Platelets;
Gestational Age;
Hematologic Tests;
Humans;
Mass Screening;
Platelet Count;
Prospective Studies;
Retinopathy of Prematurity;
Retrospective Studies;
Twins*
- From:Journal of the Korean Ophthalmological Society
2016;57(10):1592-1597
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To analyze related factors of retinopathy of prematurity by comparing between premature twins in which retinopathy developed on one twin. METHODS: A retrospective survey consisting of 13 premature twins in which retinopathy of prematurity (stage 1 or more) developed on one twin was performed. All twins were born in Kosin University Gospel Hospital. The twins were separated into two groups according to whether they had retinopathy of prematurity: the retinopathy of prematurity (ROP) group and non-ROP group. The twins' gestational age, weight, sex, Apgar score, treatments, blood tests, and neonatal complications were investigated. RESULTS: There were no significant differences between the twins except platelet count and aspartate aminotransferase. Platelet count was 191 (±46) ×10³/µL in the ROP group and 240 (±77) ×10³/µL in the non-ROP group, a significant difference (p = 0.046). Aspartate aminotransferase was 36 (±26.6) IU/L in the ROP group and 22 (±5.9) IU/L in the non-ROP group, a significant difference (p = 0.019). CONCLUSIONS: In conclusion, we found platelet count and aspartate aminotransferase to be significant factors related to development of retinopathy of prematurity. It is thought that these factors should be considered when screening for ROP, although a larger prospective study is be needed before the results can be applied in clinical practice.
