Research progress on the relationship between Porphyromonas gingivalis and the malignancy of the digestive system and possible pathogenetic mechanism.

Author: Chun-Meng WANG ¹ ; Li-Hua HONG ¹ ; Zhi-Min ZHANG ¹ ; Yu WANG ²
Author Information

1. Dept. of Endodontics, School and Hospital of Stomatology, Jilin University, Changchun 130021, China.
2. Dept. of Gastroenterology, The First Hospital of Jilin University, Changchun 130021, China.
Publication Type:Journal Article
Keywords: Porphyromonas gingivalis; digestive system malignancy; pathogenic mechanism
MeSH: Humans; Mouth Neoplasms; Periodontal Diseases; Porphyromonas gingivalis
From: West China Journal of Stomatology 2019;37(5):521-526
CountryChina
Language:Chinese
Abstract: The malignant tumors including oral cancer, colorectal cancer, pancreatic cancer, and esophageal cancer, of the digestive system are a common high-fatal malignancy. Porphyromonas gingivalis, as the most important pathogen of periodontal disease, has been gradually proved that its invasiveness occurs not only in the mouth but also in other parts of the digestive system. Moreover, the relevant pathogenic mechanism is increasingly attracting the reseachers' attention. In this study, the role and possible pathogenesis of Porphyromonas gingivalis in the digestive system are described in a systematic and comprehensive way.