A case of neuromyelitis optica spectrum disorders complicated with systemic lupus erythematosus and thymoma.
- Author:
Haijin ZHOU
1
;
Ping XIA
2
;
Xingyue HU
2
Author Information
1. Department of Neurology, the First People's Hospital of Wengling, Taizhou 317500, Zhejiang Province, China.
2. Department of Neurology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.
- Publication Type:Case Reports
- MeSH:
Anti-Inflammatory Agents;
therapeutic use;
Antibodies;
blood;
Aquaporin 4;
immunology;
Humans;
Lupus Erythematosus, Systemic;
complications;
Male;
Methylprednisolone;
therapeutic use;
Middle Aged;
Neuromyelitis Optica;
complications;
diagnostic imaging;
drug therapy;
Thymoma;
complications;
Treatment Outcome
- From:
Journal of Zhejiang University. Medical sciences
2018;47(1):71-74
- CountryChina
- Language:Chinese
-
Abstract:
A 53-year-old male patient presented with hypopsia of his right eye for 2 months and lower extremities weakness for 8 days. Thoracic MRI demonstrated a lesion at T3 level appearing as hyperintense on T2-weighted images with non-enhancement by contrast medium and demyelinating lesion was considered. Aquaporin-4-Ab was positive and the antibody titer was 1:320 in serum. The diagnosis of neuromyelitis optica spectrum disorders was made. In addition, systemic lupus erythematosus and thymoma coexisted in this patient. After methylprednisolone impact treatment, plasma exchange and immunosuppressive therapy, the right vision and lower extremities weakness of the patient were improved.
