Experimental Study on Migration Parameters of DEHP in PVC Infusion.
10.3969/j.issn.1671-7104.2019.02.016
- Author:
Jun WANG
1
;
Yan WU
1
;
Shiyong BAO
1
;
Hongqiang JIANG
1
;
Guoli SHEN
2
;
Ningqing CHEN
1
Author Information
1. Center for Medical Device Evaluation in Zhejiang Province, Hangzhou, 310009.
2. Zhejiang Crops Hospital of CAPF, Hangzhou, 310051.
- Publication Type:Journal Article
- Keywords:
DEHP;
PVC infusion;
migration parameters
- MeSH:
Diethylhexyl Phthalate;
pharmacokinetics;
Gas Chromatography-Mass Spectrometry;
Plasticizers;
pharmacokinetics;
Polyvinyl Chloride;
pharmacokinetics;
Temperature
- From:
Chinese Journal of Medical Instrumentation
2019;43(2):132-135
- CountryChina
- Language:Chinese
-
Abstract:
The work explored the DEHP migration parameters in PVC infusion in clinic,based on the previous research on the test model of DEHP migrated from PVC infusion,to assess the safety of PVC infusion.The leaching solution samples in different conditions were evaluated by analysis of the DEHP in leaching solution using GC-MS under simulated clinical transfusion way.The release behavior of DEHP was significantly affected by the storage time,storage temperature,surrounding temperature,dripping speed,sterilization process,volume of the leaching solution,and the property of the leaching solution.
