Development and homeostasis of taste buds in mammals.

Author: Xin ZHENG ¹ ; Xin XU ¹ ; Jin-Zhi HE ¹ ; Ping ZHANG ¹ ; Jiao CHEN ¹ ; Xue-Dong ZHOU ¹
Author Information

1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Conservative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Publication Type:Journal Article
Keywords: development; gustatory system; homeostasis; stem cells; taste buds
MeSH: Animals; Food; Homeostasis; Mammals; Taste; Taste Buds; growth & development
From: West China Journal of Stomatology 2018;36(5):552-558
CountryChina
Language:Chinese
Abstract: Taste is mediated by multicellular taste buds distributed throughout the oral and pharyngeal cavities. The taste buds can detect five basic tastes: sour, sweet, bitter, salty and umami, allowing mammals to select nutritious foods and avoid the ingestion of toxic and rotten foods. Once developed, the taste buds undergo continuous renewal throughout the adult life. In the past decade, significant progress has been achived in delineating the cellular and molecular mechanisms governing taste buds development and homeostasis. With this knowledges and in-depth investigations in the future, we can achieve the precise management of taste dysfunctions such as dysgeusia and ageusia.