The role of bone morphogenetic protein signaling pathway in tooth root development.

Author: Cang-Wei LIU ¹ ; Yi-Jun ZHOU ¹ ; Guang-Xing YAN ¹ ; Ce SHI ¹ ; Xue ZHANG ¹ ; Yue HU ¹ ; Xin-Qing HAO ¹ ; Huan ZHAO ¹ ; Hong-Chen SUN ¹
Author Information

1. Dept. of Oral Pathology, School and Hospital of Stomatology, Jilin University, Key Laboratory of Tooth Development and Bone Remodeling of Jilin Province, Changchun 130021, China.
Publication Type:Journal Article
Keywords: bone morphogenetic protein; epithelial root sheath; odontogenesis
MeSH: Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; physiology; Odontogenesis; Signal Transduction; Tooth; Tooth Root; growth & development
From: West China Journal of Stomatology 2018;36(5):559-563
CountryChina
Language:Chinese
Abstract: The bone morphogenetic protein (BMP) family is an important factor in the regulation of cell ular life activities and in the development of almost all tissues. BMP-mediated signaling plays an important role in tooth root development, which is a part of tooth development. Epithelial and mesenchymal interactions are involved in tooth root development, but the BMP signaling pathway has a different effect on tooth root development in epithelial and mesenchymal. This review summarizes the advances of BMP signaling in tooth root development.