Characteristics of Ventricular Function in Pulmonary Hypertension Patients
with Different Shape of Interventricular Septum:
Preliminary Study with Cardiac Magnetic Resonance Imaging.
10.3779/j.issn.1009-3419.2018.05.07
- Author:
Dan WANG
1
;
Zhang ZHANG
1
;
Fan YANG
1
;
Le ZHANG
1
;
Zhenwen YANG
2
;
Wen REN
1
;
Tielian YU
1
;
Dong LI
1
Author Information
1. Department of Radiology, Tianjin Medical University General Hospital, Tianjin 300052, China.
2. Department of Cardiovascular Disease, Tianjin Medical University General Hospital, Tianjin 300052, China.
- Publication Type:Journal Article
- Keywords:
Cardiovascular magnetic resonance;
Interventricular septum;
Pulmonary artery;
Pulmonary hypertension;
Shape;
Ventricular function
- MeSH:
Adult;
Aged;
Female;
Heart;
diagnostic imaging;
physiopathology;
Humans;
Hypertension, Pulmonary;
diagnosis;
diagnostic imaging;
physiopathology;
Lung Neoplasms;
Magnetic Resonance Imaging;
Male;
Middle Aged;
Stroke Volume;
Ventricular Function;
Ventricular Septum;
diagnostic imaging;
physiopathology
- From:
Chinese Journal of Lung Cancer
2018;21(5):397-402
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:To study the characteristics of ventricular function in Pulmonary Hypertension (PH) Patients with different shape of Interventricular Septum (IVS) by cardiac magnetic resonance (CMR).
METHODS:36 PH patients diagnosed by right heart catheterization accepted CMR. According to the morphology of IVS, the patients were divided into two groups: the non-deformation group (10 patients) and the deformation group (26 patients). The ventricular function parameters were as follows: RV and LV end-diastolic volume index (EDVI), end-systolic volume index (ESVI), stroke volume index (SVI), cardiac index (CI), ejection fraction (EF), and myocardial mass index (MMI).
RESULTS:ANOVA analysis showed that the differences of RVEDVI, RVESVI, RVSVI, RVCI, RVEF, RVMMI, LVEDVI, LVESVI, LVSVI and LVCI were significant among the three groups. Compared with control group, RVSVI (P=0.017), RVEF (P<0.001), LVEDVI (P=0.048) and LVSVI (P=0.015) decreased in IVS non-deformation group. Compared with IVS non-deformation group, RVEDVI (P<0.001), RVESVI (P<0.001), RVCI (P=0.002) and RVMMI (P=0.017) were increased in IVS deformation group; while RVEF (P=0.001), LVEDVI (P=0.003), LVSVI (P<0.001) and LVCI (P=0.029) were decreased. Compared with the control group, RVEDVI (P<0.001), RVESVI (P<0.001), RVCI (P=0.004) and RVMMI (P=0.003) were increased in the IVS deformation group, while RVEF (P<0.001), LVEDVI (P<0.001), LVESVI (P<0.001), LVSVI (P<0.001), LVCI (P<0.001) were decreased.
CONCLUSIONS:Ventricular function is different in PH Patients with different IVS shape. The IVS shape can represent the changes of ventricular function in PH patients.
